Changed dietary habits in Western countries such as reduced fiber intake represent an important lifestyle factor contributing to the increase in inflammatory immune-mediated diseases.The mode of action of beneficial fiber effects is not fully elucidated, but short-chain fatty acids (SCFA) and gut microbiota have been implicated.The aim of this stud
Evaluation of a national surveillance system for mortality alerts: a mixed-methods study
Background: Since 2007, Imperial College London has generated monthly mortality alerts, based on statistical process control charts and using routinely collected hospital administrative data, for all English acute NHS hospital trusts.The impact of this system has not yet been studied.Objectives: To improve understanding of mortality alerts and eval
Engineered T cells from induced pluripotent stem cells: from research towards clinical implementation
Induced pluripotent stem cell (iPSC)-derived T (iT) cells represent a groundbreaking frontier in adoptive cell therapies with engineered T cells, poised to overcome pivotal limitations associated with conventional manufacturing methods.iPSCs offer an off-the-shelf source of therapeutic T cells with the potential for infinite expansion and straightf
Study of antibiotic resistance of staph aureus and coagulase negative staphylococci isolated from patient samples
Introduction: Drug resistant Staphylococci are the most important agents of nosocomial infections.In this survey, effect of different antibiotics on these bacteria and their drug resistance was investigated.Methods: The MINT study included 500 strains of Staphylococci.Minimum Inhibitory Concentrations of all antibiotics was determined by the broth